A RETROSPECTIVE STUDY OF HISTOMORPHOLOGICAL SPECTRUM OF HANSEN’S DISEASE IN A TERTIARY CARE CENTRE OF BARABANKI AREA

Objectives: Hansen’s disease is a chronic granulomatous infectious caused by Mycobacterium leprae. Early detection essential to prevent the disease’s spread and disability. Due multitude of morphologies, it may be difficult accurately diagnose certain cases based solely on clinical signs; therefore, histopathology crucial for definitive diagnosis. The study aims investigate various histological forms leprosy over year in tertiary care hospital. Methods: It was retrospective that included 25 were clinically histopathologically diagnosed from July 2021 August 2022 center. Results: majority second decade with male predominance (M:F=1.5:1). According histomorphology, tuberculoid most common type (36%), followed borderline (24%), lepromatous (16%), (8%), histoid (4%), indeterminate (4%). Ziehl–Neelsen staining acid-fast bacilli demonstrated positivity 8 cases. Conclusion: As spectrum diverse, gold standard diagnosis key tool obtaining conclusive